Bus from Liverpool to Manchester City Centre
9 direct routes · 60–110 min · first bus 06:00, last bus 21:50 (weekdays); night services 170 and 421 run 01:45–19:30.
Next buses to Manchester City Centre as of 12:14
Scheduled times at the boarding stop in Liverpool, from the operators' timetables — they update automatically. Open the stop for live tracking.
Direct routes
| Route | Operator | Journey time | Weekday journeys | Days | First | Last | Board at | Get off at | Calls at |
|---|---|---|---|---|---|---|---|---|---|
| 170 | National Express | ~105 min | 10 | Sat 16 · Sun 16 | 02:30 | 19:30 | Liverpool ONE Bus Station (Stand 1) | Manchester Central Coach Station | Old Swan |
| 811 | National Express | ~90 min | 6 | Fridays only | 07:00 | 20:00 | Liverpool ONE Bus Station (Stand 1) | Manchester Central Coach Station | Old Swan |
| 541 | National Express | ~85 min | 4 | Sat 4 · Sun 4 | 06:00 | 14:20 | Liverpool ONE Bus Station (Stand 1) | Manchester Central Coach Station | Old Swan |
6 occasional services — once or twice a day · 540, 819, UK072, UK074, 802, 421
Often school, college or market-day journeys — check the route before relying on one.
| Route | Operator | Journey time | Weekday journeys | Days | First | Last | Board at | Get off at | Calls at |
|---|---|---|---|---|---|---|---|---|---|
| 540 | National Express | ~95 min | 2 | Sat 4 · Sun 4 | 13:20 | 16:25 | Liverpool ONE Bus Station (Stand 1) | Manchester Central Coach Station | Old Swan |
| 819 | National Express | ~70 min | 2 | Fridays only | 08:05 | 11:05 | Liverpool ONE Bus Station (Stand 1) | Manchester Central Coach Station | — |
| UK072 | FlixBus | ~110 min | 2 | Sat 2 · Sun 2 | 10:30 | 18:45 | Liverpool ONE Bus Station (Stand 6) | Shudehill Interchange (Stand G) | — |
| UK074 | FlixBus | ~100 min | 2 | Sat 2 · Sun 2 | 12:10 | 21:50 | Liverpool ONE Bus Station (Stand 6) | Shudehill Interchange (Stand G) | — |
| 802 | National Express | ~65 min | 2 | Fridays only | 12:10 | 16:10 | Liverpool ONE Bus Station (Stand 1) | Manchester Central Coach Station | — |
| 421 | National Express | ~60 min | 1 | Sat 1 · Sun 1 | 01:45 | 01:45 | Liverpool ONE Bus Station (Stand 1) | Manchester Central Coach Station | Old Swan |
Times are for the first boarding point in Liverpool on each route's weekday timetable — open the route for the full timetable, live map and every stop.
The same number runs elsewhere in the UK — see every 170 bus, 811 bus, 541 bus, 540 bus, 819 bus, 802 bus or 421 bus timetable.
Frequently asked questions
Which bus goes from Liverpool to Manchester City Centre?
9 routes run directly from Liverpool to Manchester City Centre: the 170 (National Express), the 811 (National Express), the 541 (National Express), the 540 (National Express), the 819 (National Express), the UK072 (FlixBus), the UK074 (FlixBus), the 802 (National Express), the 421 (National Express). The most frequent is the 170, 10 times each weekday — board at Liverpool ONE Bus Station (Stand 1) and get off at Manchester Central Coach Station, about 105 minutes.
How long does the bus take from Liverpool to Manchester City Centre?
Between 60 minutes on the 421 and 110 on the UK072, depending on which route you catch and on traffic. It calls at Old Swan on the way.
What time is the first and last bus from Liverpool to Manchester City Centre?
On weekdays the first direct bus leaves around 06:00 and the last around 21:50 — and night services 170 and 421 run 01:45–19:30. Check the route timetables for weekends.
How much is the bus from Liverpool to Manchester City Centre?
This is a long-distance coach service, so the England £3 bus fare cap does not apply — nor do local bus tickets or passes. Coach operators set their own fares and price by demand, so booking further ahead is usually much cheaper than buying on the day.