🚌 Bus from Liverpool to Manchester City Centre
6 direct routes · about 105 min · first bus 02:30, last bus 19:30 (weekdays).
Direct routes
| Route | Operator | Journey time | Weekday journeys | First | Last | Board at |
|---|---|---|---|---|---|---|
| 170 | National Express | ~105 min | 20 | 02:30 | 19:30 | Liverpool ONE Bus Station (Stand 1) |
| 541 | National Express | ~85 min | 7 | 06:00 | 14:35 | Liverpool ONE Bus Station (Stand 1) |
| 540 | National Express | ~85 min | 6 | 05:45 | 16:25 | Liverpool ONE Bus Station (Stand 1) |
| UK021 | FlixBus | ~80 min | 1 | 18:00 | 18:00 | Liverpool ONE Bus Station (Stand 6) |
| 421 | National Express | ~60 min | 1 | 01:45 | 01:45 | Liverpool ONE Bus Station (Stand 1) |
| N18 | National Express | ~60 min | 1 | 09:15 | 09:15 | Liverpool ONE Bus Station (Stand 1) |
Times are for the first boarding point in Liverpool on each route's weekday timetable — open the route for the full timetable, live map and every stop.
Frequently asked questions
Which bus goes from Liverpool to Manchester City Centre?
6 routes run directly from Liverpool to Manchester City Centre: the 170 (National Express), the 541 (National Express), the 540 (National Express), the UK021 (FlixBus), the 421 (National Express), the N18 (National Express).
How long does the bus take from Liverpool to Manchester City Centre?
Around 105 minutes on the 170, depending on time of day and traffic.
What time is the first and last bus from Liverpool to Manchester City Centre?
On weekdays the first direct bus (the 170) leaves around 02:30 and the last around 19:30. Check the route timetable for weekends.
How much is the bus from Liverpool to Manchester City Centre?
Most single fares in England are capped at £3 until 31 December 2026, then £2 from 1 January 2027.